Friday, October 12, 2007

ANTIBACTERIAL PREPARATIONS SHOWING PHARMACOLOGICAL CLASS WITH TRADE NAMES

DR. AJAY KUMAR GOILA, CMO (NFSG), DEPARTMENT OF ANAESTHESIOLOGY

DR. R.M.L.HOSPITAL, NEW DELHI


b lactam antibiotics

Penicillins-

  • b Lactamase susceptible

1. Narrow spectrum- Penicillin G

2. Enteric active- Ampicillin.

3. Enteric active and anti pseudomonal- Carbenicillin, Ticarcillin, Mezlocillin, Azlocillin Piperacillin (Pipracil)

  • b lactamase resistant (b lactamase stable)(Penicillinase Resistant Penicillin)

1. Antistaphylococcal-Methicillin, Oxacillin, Nafcillin

2. Combined with b lactamase inhibitors-

Ticarcilln Plus Clavulanic Acid (Timentin)

Ampicillin Plus Sulbactum (Sulbacin)

Piperacillin Plus Tazobactum (Zosyn)

Cefoperazone Plus Sulbactum (Magnex)

Amoxycillin Plus Clavulanic Acid (Augmentin)

Cephalosporins-

1. First Generation-Cephazolin (Azolin),Cephalothin,Cephapirin

2. Second Generation-

Haemophilus Active-Cefamandole, Cefuroxime(Supacef), Cefonicid, Ceforanide

Bacteroids Active-(Aerobic Anaerobic Gram Negative) Cefoxitin, Cefotetan, Cefmetazole

3. Third generation-

  1. Extended Spectrum- Ceftriaxone (Monocef),Cefotaxime (Claforan, Omnatax),Ceftizoxime (Cefizox)
  1. Extended Spectrum And Anti Pseudomonal- Ceftazidime (Ceftidin),

    Cefoperazone (Magnamycin),Cefepime, Cefoperazone Plus Sulbactum (Magnex)

    Carbapanems – community acquired gram positive and gram negative resistant to b lactamase

Imipenem, Meropenem (Meronem)

Monobactums – Aztreonam- only aerobic gram negative enterobacteriacae


 

AMINOGLYCOSIDES- aerobic gram negative

Amikacin (Amicin),Gentamycin (Genticyn), ,Tobramycin (Tobraneg)Kanamycin (Kancin),Netilmicin (Netromycin),Spectinomicin (Trobicin),Streptomycin (Ambistryn-S)


 

GLYCOPEPTIDES aerobic and anaerobic gram negative

Teicoplanin(Targocid), Vancomycin(Vancocin)


 

MACROLIDES- gram negative anaerobes

Azithromycin(Azithral), Clarithromycin (Claribed), Erythromycin (Altocin), Spiramycin (Rovamycin), Roxithromycin (Roxid)


 

NITROIMIDAZOLE gram negative anaerobes

Metronidazole (Flagyl), Ornidazole (Oniz), Tinidazole (Fasigyn)


 

LINCOSAMIDE Aerobic Gram Positive (Not Enterococci), Both Anaerobic Gram Positive Bacilli And Cocci.

Clindamycin (Dalacin), Lincomycin (Lynx)


 

QUINOLONES aerobic gram negative and positive bacilli and cocci

Nalidix Acid (Gramoneg), Ciprofloxacin (Ciplox), Gatifloxacin (Zyquin), Lomefloxacin (Lomef), Levofloxacin (Tavanic), Norfloxacin(Norflox), Ofloxacin (Zanocin, Tarivid), Pefloxacin (Pelox), Sparfloxacin (Sparx)


 

Corresponding Author- DR. AJAY KUMAR GOILA

E mail: ajaygo9@vsnl.com Phone No: 9810145822

4 comments:

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